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1

Efficacy and Safety of the Farnesoid X Receptor Agonist Obeticholic Acid in Patients With Type 2 Diabetes and Nonalcoholic Fatty Liver Disease

Mudaliar, Sunder, Henry, Robert R., Sanyal, Arun J., Morrow, Linda, Marschall, Hanns–Ulrich, Kipnes, Mark, Adorini, Luciano, Sciacca, Cathi I., Clopton, Paul, Castelloe, Erin, Dillon, Paul, Pruzanski,

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 659 KB

english, 2013

2

Vitamin D Receptor Agonists, Cancer and the Immune System: An Intricate Relationship

Adorini, Luciano, Daniel, Kenn, Penna, Giuseppe

Journal:

Current Topics in Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 104 KB

english, 2006

3

The vitamin D receptor as a therapeutic target

Campbell, Moray J, Adorini, Luciano

Journal:

Expert Opinion on Therapeutic Targets

Year:

2006

Language:

english

File:

PDF, 226 KB

english, 2006

4

Inhibition of Th1 development and treatment of chronic-relapsing experimental allergic encephalomyelitis by a non-hypercalcemic analogue of 1,25-dihydroxyvitamin D3

Frank Mattner, Simona Smiroldo, Francesca Galbiati, Marc Muller, Pietro Di Lucia, Pietro L. Poliani, Gianvito Martino, Paola Panina-Bordignon, Luciano Adorini

Journal:

European Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 544 KB

english, 2000

5

Beneficial effects of bile acid receptor agonists in pulmonary disease models

Comeglio, Paolo, Morelli, Annamaria, Adorini, Luciano, Maggi, Mario, Vignozzi, Linda

Journal:

Expert Opinion on Investigational Drugs

Year:

2017

Language:

english

File:

PDF, 1.53 MB

english, 2017

6

Manipulation of the Th1/Th2 Cell Balance: An Approach to Treat Human Autoimmune Diseases?

Adorini, Luciano, Guery, Jean-Charles, Trembleau, Sylvie

Journal:

Year:

1996

Language:

english

File:

PDF, 1.48 MB

english, 1996

7

Efficacy of a potent and safe vitamin D receptor agonist for the treatment of inflammatory bowel disease

Gilles Laverny, Giuseppe Penna, Stefania Vetrano, Carmen Correale, Manuela Nebuloni, Silvio Danese, Luciano Adorini

Journal:

Immunology Letters

Year:

2010

Language:

english

File:

PDF, 1.32 MB

english, 2010

8

Vitamin D Receptor Agonists in the Treatment of Autoimmune Diseases: Selective Targeting of Myeloid but Not Plasmacytoid Dendritic Cells

Giuseppe Penna, Susana Amuchastegui, Gilles Laverny, Luciano Adorini

Journal:

Journal of Bone and Mineral Research

Year:

2007

Language:

english

File:

PDF, 444 KB

english, 2007

9

Encyclopedia of Immunology || Immunodominance

Adorini, Luciano

Year:

1998

File:

PDF, 267 KB

1998

10

Vitamin D || Control of Adaptive Immunity by Vitamin D Receptor Agonists

Adorini, Luciano

Year:

2011

Language:

english

File:

PDF, 575 KB

english, 2011

11

Obeticholic acid and INT-767 modulate collagen deposition in a NASH in vitro model

Anfuso, Beatrice, Tiribelli, Claudio, Adorini, Luciano, Rosso, Natalia

Journal:

Scientific Reports

Year:

2020

File:

PDF, 1.94 MB

2020

12

Obeticholic acid improves fetal bile acid profile in a mouse model of gestational hypercholanemia

Pataia, Vanessa, McIlvride, Saraid, Papacleovoulou, Georgia, Ovadia, Caroline, McDonald, Julie A. K., WahlstrÃ¶m, Annika, Jansen, Eugene, Adorini, Luciano, Shapiro, David, Marchesi, Julian R., Marscha

Journal:

American Journal of Physiology - Gastrointestinal and Liver Physiology

Year:

2020

File:

PDF, 4.82 MB

2020

13

Farnesoid X Receptor Activation Improves Erectile Function in Animal Models of Metabolic Syndrome and Diabetes

Linda Vignozzi, Annamaria Morelli, Sandra Filippi, Paolo Comeglio, Aravinda K. Chavalmane, Matilde Marchetta, Mariateresa Toce, Ravit Yehiely-Cohen, Gabriella B. Vannelli, Luciano Adorini, Mario Maggi

Journal:

The Journal of Sexual Medicine

Year:

2011

Language:

english

File:

PDF, 2.12 MB

english, 2011

14

A miniaturized in vitro diffusion culture system

Erich F. Eipert, Luciano Adorini, Jacques Couderc

Journal:

Journal of Immunological Methods

Year:

1978

Language:

english

File:

PDF, 722 KB

english, 1978

15

A microcomputer program for hydrophilicity and amphipathicity analysis of protein antigens

Alessandro Sette, Gino Doria, Luciano Adorini

Journal:

Molecular Immunology

Year:

1986

Language:

english

File:

PDF, 397 KB

english, 1986

16

The Role of IL-12 in the Pathogenesis of Thl Cell-Mediated Autoimmune Diseases

LUCIANO ADORINI, SILVIA GREGORI, JEANNE MAGRAM, SYLVIE TREMBLEAU

Journal:

Annals of the New York Academy of Sciences

Year:

1996

Language:

english

File:

PDF, 517 KB

english, 1996

17

A Dual Agonist of Farnesoid X Receptor (FXR) and the G protein-coupled Receptor TGR5, INT-767, Slows Down Age-Related Kidney Disease in Mice

Wang, Xiaoxin X., Luo, Yuhuan, Wang, Dong, Adorini, Luciano, Pruzanski, Mark, Dobrinskikh, Evgenia, Levi, Moshe

Journal:

Journal of Biological Chemistry

Year:

2017

Language:

english

File:

PDF, 1.25 MB

english, 2017

18

Enhancement of helper and suppressor T cell activities by thymosin α1 injection in old mice

Daniela Frasca, Luciano Adorini, Gino Doria

Journal:

Immunopharmacology

Year:

1985

Language:

english

File:

PDF, 663 KB

english, 1985

19

Farnesoid X receptor activation improves erectile dysfunction in models of metabolic syndrome and diabetes

Annamaria Morelli, Linda Vignozzi, Mario Maggi, Luciano Adorini

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Year:

2011

Language:

english

File:

PDF, 850 KB

english, 2011

20

Dendritic cell tolerogenicity: a key mechanism in immunomodulation by vitamin D receptor agonists

Luciano Adorini, Giuseppe Penna

Journal:

Human Immunology

Year:

2009

Language:

english

File:

PDF, 910 KB

english, 2009

21

Inhibition of T cell activation by MHC blockade: A possible strategy for immunointervention in autoimmune diseases

Adorini, Luciano

Journal:

Journal of Autoimmunity

Year:

1992

Language:

english

File:

PDF, 619 KB

english, 1992

22

Megatrends in bile acid receptor research

Adorini, Luciano, Schoonjans, Kristina, Friedman, Scott L.

Journal:

Hepatology Communications

Year:

2017

Language:

english

File:

PDF, 115 KB

english, 2017

23

Microbiota-driven gut vascular barrier disruption is a prerequisite for non-alcoholic steatohepatitis development

Mouries, Juliette, Brescia, Paola, Silvestri, Alessandra, Spadoni, Ilaria, Sorribas, Marcel, Wiest, Reiner, Mileti, Erika, Galbiati, Marianna, Invernizzi, Pietro, Adorini, Luciano, Penna, Giuseppe, Re

Journal:

Journal of Hepatology

Year:

2019

File:

PDF, 1.35 MB

2019

24

IL-12 receptor regulation in IL-12-deficient BALB / c and C57BL / 6 mice

Francesca Galbiati, Lars Rogge, Luciano Adorini

Journal:

European Journal of Immunology

Year:

2000

Language:

english

File:

PDF, 151 KB

english, 2000

25

Inhibition of T cell response with peptides is influenced by both peptide-binding specificity of major histocompatibility complex molecules and susceptibility of T cells to blocking

Paul V. Lehmann, Francis Cardinaux, Ettore Appella, Simone Muller, Fiorenza Falcioni, Luciano Adorini, Zoltan A. Nagy

Journal:

European Journal of Immunology

Year:

1989

Language:

english

File:

PDF, 646 KB

english, 1989

26

Calcitriol derivatives with two different side-chains at C-20. Part 4: Further chain modifications that alter VDR-dependent monocytic differentiation potency in human leukemia cells

Edward Garay, Pawel Jankowski, Paulo Lizano, Stanislaw Marczak, Hubert Maehr, Luciano Adorini, Milan R. Uskokovic, George P. Studzinski

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 365 KB

english, 2007

27

T cell independent induction of antigen specific suppression of the antibody response

Luciano Adorini, Diana Boraschi, Gino Doria

Journal:

International Journal of Clinical & Laboratory Research

Year:

1979

Language:

english

File:

PDF, 607 KB

english, 1979

28

Metabolic syndrome induces inflammation and impairs gonadotropin-releasing hormone neurons in the preoptic area of the hypothalamus in rabbits

Morelli, Annamaria, Sarchielli, Erica, Comeglio, Paolo, Filippi, Sandra, Vignozzi, Linda, Marini, Mirca, Rastrelli, Giulia, Maneschi, Elena, Cellai, Ilaria, Persani, Luca, Adorini, Luciano, Vannelli,

Journal:

Molecular and Cellular Endocrinology

Year:

2014

Language:

english

File:

PDF, 3.12 MB

english, 2014

29

BXL-628, a vitamin D receptor agonist effective in benign prostatic hyperplasia treatment, prevents RhoA activation and inhibits RhoA/Rho kinase signaling in rat and human bladder

Annamaria Morelli, Linda Vignozzi, Sandra Filippi, Gabriella Barbara Vannelli, Stefano Ambrosini, Rosa Mancina, Clara Crescioli, Silvia Donati, Benedetta Fibbi, Enrico Colli, Luciano Adorini, Mario Ma

Journal:

Year:

2007

Language:

english

File:

PDF, 357 KB

english, 2007

30

Basic strategies of the immune system in the regulation of antibody response

Luciano Adorini

Journal:

International Journal of Clinical & Laboratory Research

Year:

1980

Language:

english

File:

PDF, 1.23 MB

english, 1980

31

Lysozyme-induced T-suppressor cells and antibodies have a predominant idiotype

Harvey, Michael A., Adorini, Luciano, Miller, Alexander, Sercarz, Eli E.

Journal:

Year:

1979

File:

PDF, 594 KB

1979

32

Seminal Plasma Cytokines and Chemokines in Prostate Inflammation: Interleukin 8 as a Predictive Biomarker in Chronic Prostatitis/Chronic Pelvic Pain Syndrome and Benign Prostatic Hyperplasia

Giuseppe Penna, Nicola Mondaini, Susana Amuchastegui, Selene Degli Innocenti, Marco Carini, Gianluca Giubilei, Benedetta Fibbi, Enrico Colli, Mario Maggi, Luciano Adorini

Journal:

European Urology

Year:

2007

Language:

english

File:

PDF, 1.32 MB

english, 2007

33

Inhibition of prostate growth and inflammation by the vitamin D receptor agonist BXL-628 (elocalcitol)

Luciano Adorini, Giuseppe Penna, Susana Amuchastegui, Chiara Cossetti, Francesca Aquilano, Roberto Mariani, Benedetta Fibbi, Annamaria Morelli, Milan Uskokovic, Enrico Colli, Mario Maggi

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2007

Language:

english

File:

PDF, 297 KB

english, 2007

34

The ependymal route to the CNS: an emerging gene-therapy approach for MS

Gianvito Martino, Roberto Furlan, Giancarlo Comi, Luciano Adorini

Journal:

Trends in Immunology

Year:

2001

Language:

english

File:

PDF, 997 KB

english, 2001

35

Immunomodulatory effects of vitamin D receptor ligands in autoimmune diseases

Luciano Adorini

Journal:

International Immunopharmacology

Year:

2002

Language:

english

File:

PDF, 134 KB

english, 2002

36

Inhibition of Acute and Chronic Allograft Rejection in Mouse Models by BXL-628, a Nonhypercalcemic Vitamin D Receptor Agonist

Amuchastegui, Susana, Daniel, Kenn C., Adorini, Luciano

Journal:

Transplantation Journal

Year:

2005

Language:

english

File:

PDF, 705 KB

english, 2005

37

Cardiopulmonary protective effects of the selective FXR agonist obeticholic acid in the rat model of monocrotaline-induced pulmonary hypertension

Vignozzi, Linda, Morelli, Annamaria, Cellai, Ilaria, Filippi, Sandra, Comeglio, Paolo, Sarchielli, Erica, Maneschi, Elena, Vannelli, Gabriella Barbara, Adorini, Luciano, Maggi, Mario

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2016

Language:

english

File:

PDF, 830 KB

english, 2016

38

The FXR agonist obeticholic acid decreases matrix metalloproteinase activity via RECK and TIMP modulation in hepatic ischemia/reperfusion injury

Di Pasqua, Laura Giuseppina, Palladini, Giuseppina, Berardo, Clarissa, Siciliano, Veronica, Cagna, Marta, Adorini, Luciano, Richelmi, Plinio, Ferrigno, Andrea, Vairetti, Mariapia

Journal:

Journal of Hepatology

Year:

2020

File:

PDF, 384 KB

2020

39

IL-12: a key cytokine in immune regulation

Alan G. Lamont, Luciano Adorini

Journal:

Immunology Today

Year:

1996

Language:

english

File:

PDF, 756 KB

english, 1996

40

Structural requirements for the interaction between class II MHC molecules and peptide antigens

Alessandro Sette, Søren Buus, Ettore Appella, Luciano Adorini, Howard M. Grey

Journal:

Immunologic Research

Year:

1990

Language:

english

File:

PDF, 669 KB

english, 1990

41

TGR5 Activation Inhibits Atherosclerosis by Reducing Macrophage Inflammation and Lipid Loading

Thijs W.H. Pols, Mitsunori Nomura, Taoufiq Harach, Giuseppe Lo Sasso, Maaike H. Oosterveer, Charles Thomas, Giovanni Rizzo, Antimo Gioiello, Luciano Adorini, Roberto Pellicciari, Johan Auwerx, Kristin

Journal:

Cell Metabolism

Year:

2011

Language:

english

File:

PDF, 1.09 MB

english, 2011

42

Computerized data analysis in cellular immunology. Enhancement and suppression of immune responses

Alessandro Sette, Luciano Adorini, Camillo Mancini, Ettore Marubini, Gino Doria

Journal:

Journal of Immunological Methods

Year:

1988

Language:

english

File:

PDF, 519 KB

english, 1988

43

Hepatic carboxylesterase 1 is essential for both normal and farnesoid X receptor-controlled lipid homeostasis

Xu, Jiesi, Li, Yuanyuan, Chen, Wei-Dong, Xu, Yang, Yin, Liya, Ge, Xuemei, Jadhav, Kavita, Adorini, Luciano, Zhang, Yanqiao

Journal:

Year:

2014

Language:

english

File:

PDF, 1.06 MB

english, 2014

44

Vitamin D receptor agonists as anti-inflammatory agents

Adorini, Luciano, Amuchastegui, Susana, Corsiero, Elisa, Laverny, Gilles, Le Meur, Thomas, Penna, Giuseppe

Journal:

Expert Review of Clinical Immunology

Year:

2007

Language:

english

File:

PDF, 404 KB

english, 2007

45

196 Monocyte-Dependent and -Independent Modulatory Effects of Vitamin D3 on X4 and R5 HIV-1 Replication in IL-2 Stimulated PBMC

Alfano, Massimo, Rizzi, Chiara, Penna, Giuseppe, Adorini, Luciano, Poli, Guido

Journal:

JAIDS Journal of Acquired Immune Deficiency Syndromes

Year:

2009

Language:

english

File:

PDF, 1.01 MB

english, 2009

46

Obeticholic acid ameliorates dyslipidemia but not glucose tolerance in a mouse model of gestational diabetes

McIlvride, Saraid, Nikolova, Vanya, Fan, Hei Man, McDonald, Julie A. K., Wahlström, Annika, Bellafante, Elena, Jansen, Eugene, Adorini, Luciano, Shapiro, David, Jones, Peter, Marchesi, Julian R., Mars

Journal:

American Journal of Physiology-Endocrinology and Metabolism

Year:

2019

Language:

english

File:

PDF, 694 KB

english, 2019

47

Analysis of lysozyme-specific immune responses by synthetic peptides. I. Characterization of antibody and T cell-mediated responses to the N-terminal peptide of hen egg-white lysozyme

Alessandro Sette, Vittorio Colizzi, Ettore Appella, Gino Doria, Luciano Adorini

Journal:

European Journal of Immunology

Year:

1986

Language:

english

File:

PDF, 683 KB

english, 1986

48

Pyrazole[3,4-e][1,4]thiazepin-7-one derivatives as a novel class of Farnesoid X Receptor (FXR) agonists

Maura Marinozzi, Andrea Carotti, Emanuele Sansone, Antonio Macchiarulo, Emiliano Rosatelli, Roccaldo Sardella, Benedetto Natalini, Giovanni Rizzo, Luciano Adorini, Daniela Passeri, Francesca De Franco

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.39 MB

english, 2012

49

Dendritic cells as key targets for immunomodulation by Vitamin D receptor ligands

Luciano Adorini, Giuseppe Penna, Nadia Giarratana, Andrea Roncari, Susana Amuchastegui, Kenn C. Daniel, Milan Uskokovic

Journal:

The Journal of Steroid Biochemistry and Molecular Biology

Year:

2004

Language:

english

File:

PDF, 80 KB

english, 2004

50

Human Bladder as a Novel Target for Vitamin D Receptor Ligands

Crescioli, Clara, Morelli, Annamaria, Adorini, Luciano, Ferruzzi, Pietro, Luconi, Michaela, Vannelli, Gabriella Barbara, Marini, Mirca, Gelmini, Stefania, Fibbi, Benedetta, Donati, Silvia, Villari, Do

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2005

Language:

english

File:

PDF, 668 KB

english, 2005

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